李莹莹
发布时间:2021-03-28 10:08:27
李莹莹 Yingying Li
讲师 硕士生导师
办公电话:0411-85827065
邮箱:liyingying16@163.com

履历

  • 上海交通大学 博士(2008-2013)
  • 辽宁师范大学 讲师(2013-)
  • 辽宁师范大学 硕士生导师(2015-)

 

研究方向

  • 肠道微生物与宿主免疫系统互作:以脊椎动物适应性免疫发育研究的“活化石”---七鳃鳗为研究对象,探究七鳃鳗肠道微生物调控其适应性系统发育的分子机制
  • 招生专业:生物学、细胞生物学、微生物学硕士研究生

 

代表性论文

  • Yingying Li*, Nan Wang, Jingrui Zhang, Yihua Zhao, Yang Xu, Qingwei Li*. Role of Aeromonas sp. involving in adaptive immune response of adult Lethenteron reissneri. Aquaculture, 2021, 736120, DOI:10.1016/j.aquaculture.2020.736120.
  • Yingying Li, Yu Zuo, Wenying Zhang, Yihua Zhao, Qingwei Li*. A novel protein L-cofilin2 identified in Lampetra morii with roles of immune response and cell proliferation promotion. ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2019, 51 (12): 1300-1303.
  • Yu Zuo, Wenfang Xie, Tiesong Li, Qingwei Li*, Yingying Li*. Bacterial community composition in the gut content of Lampetra japonica revealed by 16S rRNA gene pyrosequencing. PLoS One, 2017, 12 (12): e0188919.
  • Yingying Li, Wenying Zhang, Yu Zuo, Ting Zhu, Yue Pang, Tiesong Li, Qingwei Li*. Label-Free Quantitative Proteomic Reveals Differentially Expressed Proteins in Aeromonas-Immunostimulated Leukocytes of Lampetra japonica. Current Microbiology, 2018, 75 (7): 934-941.
  • Yingying Li, Wenfang Xie, Qingwei Li*. Characterisation of the bacterial community structures in the intestine of Lampetra morii. Antonie Van Leeuwenhoek, 2016, 109 (7): 979-986.
  • Yingying Li, Kai Dou, Shigang Gao, Jianan Sun, Meng Wang, Kehe Fu, Chuanjin Yu, Qiong Wu, Yaqian Li, Jie Chen*. Impacts on silkworm larvae midgut proteomics by transgenic Trichoderma strain and analysis of glutathione S-transferase sigma 2 gene essential for anti-stress response of silkworm larvae. Journal of Proteomics, 2015, 126: 218-227.
  • Yingying Li, Kehe Fu, Shigang Gao, Qiong Wu, Lili Fan, Yaqian Li, Jie Chen*. Impact on bacterial community in midguts of the Asian corn borer larvae by transgenic Trichoderma strain overexpressing a heterologous chit42 gene with chitin-binding domain. PLoS One, 2013, 8 (2): e55555.
  • Yingying Li, Kehe Fu, Shigang Gao, Qiong Wu, Lili Fan, Jie Chen*. Increased virulence of transgenic Trichoderma koningi strains to the Asian corn borer larvae by overexpressing heterologous chit42 gene with chitin-binding domains. J Environ Sci Health B, 2013, 48 (5): 376-383.
  • Yingying Li, Jun Tang, Kehe Fu, Shigang Gao, Qiong Wu, Jie Chen*. Construction of transgenic Trichoderma koningi with chit42 of Metarhizium anisopliae and analysis of its activity against the Asian corn borer. J Environ Sci Health B, 2012, 47 (7): 622-630.
  • 张新妍, 张文颖,李庆伟,李莹莹*. 日本七鳃鳗L-STAT3的克隆及体内外表达分析. 中国细胞生物学学报, 2020, 42 (9): 1598-1605.
  • 解文放, 左玉, 李庆伟*, 李莹莹*. 动物肠道菌群与宿主肠道免疫系统相互作用的研究进展. 中国细胞生物学学报, 2017, 11: 1467-1472.
  • 李莹莹, 解文放, 朱婷, 李庆伟*. 东北七鳃鳗肠道应答气单胞菌免疫刺激相关蛋白的鉴定. 中国生物化学与分子生物学报, 2016, 32 (11): 1256-1263.

 

开设课程

  • 分子克隆技术(本科生)
  • 文献检索与论文写作(本科生)
  • 蛋白质组学(本科生)
  • 专业外语(研究生)

 

科研课题

  • 肠道共生细菌与七鳃鳗可变淋巴细胞受体VLRA、VLRC交联对话(Cross-talk)机制研究,31500106,国家自然科学基金青年科学基金(主持人)
  • 肠道共生细菌调控七鳃鳗类淋巴细胞分化机制研究,2016M590233,中国博士后科学基金面上项目一等资助(主持人)
  • 肠道共生细菌调控七鳃鳗类淋巴细胞分化机制研究,L201683674,辽宁省教育厅一般项目(主持人)
  • 肠道共生细菌调控七鳃鳗肠道VLRA+、VLRC+类淋巴细胞分化机制研究,201501107,辽宁省科技厅博士启动基金(主持人)
  • 肠道共生细菌对于七鳃鳗抵御病原体侵染的作用,2019RQ065,大连市高层次人才创新支持计划项目(主持人)
  • 脂多糖诱导七鳃鳗髓样细胞免疫相关基因的鉴定与功能研究,LS2014L009,辽宁师范大学青年基金(主持人)
 

荣誉奖励

 
 
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