履历

研究方向

代表性论文

• Li Y, Yu Y, Zhang L, Li Y, Gou M^*. Integrated transcriptomic and metabolomic analyses reveal the toxic effects of dimethoate on green vegetable soya bean seedlings. Gene. 2024 Jan 15;891:147799. doi: 10.1016/j.gene.2023.147799. Epub 2023 Sep 20. PMID: 37739194.
• Gou M, Duan X, Li J, Wang Y, Li Q, Pang Y, Dong Y. Spatial Metabolomics Reveals the Multifaceted Nature of Lamprey Buccal Gland and Its Diverse Mechanisms for Blood-Feeding. Commun Biol. 2023 Aug 28;6(1):881. doi: 10.1038/s42003-023-05250-x. PMID: 37640823; PMCID: PMC10462737.
• Wang Y, Dong Y, Duan X, Luan Y, Li Q, Pang Y, Sun F, Gou M^*. A complete prostaglandin pathway from synthesis to inactivation in the oral gland of the jawless vertebrate lamprey, Lethenteron camtschaticum. Dev Comp Immunol. 2023 Nov;148:104903. doi: 10.1016/j.dci.2023.104903. Epub 2023 Aug 3. PMID: 37541459.
• Wang Y, Sun F, Wang Z, Duan X, Li Q, Pang Y, Gou M^*. Peptidomics Analysis Reveals the Buccal Gland of Jawless Vertebrate Lamprey as a Source of Multiple Bioactive Peptides. Mar Drugs. 2023 Jun 29;21(7):389. doi: 10.3390/md21070389. PMID: 37504920; PMCID: PMC10381800.
• Luan Y, Wang Y, Zhang W, Duan X, Su P, Li Q, Pang Y, Gou M^*. Identification and characterization of tryptophan-kynurenine pathway-related genes involving lamprey (Lampetra japonica) innate immunity. Fish Shellfish Immunol. 2023 Sep;140:108967. doi: 10.1016/j.fsi.2023.108967. Epub 2023 Jul 23. PMID: 37488041.
• Duan X, Pan T, Wang Z, Pu Y, Li Q, Pang Y, Xu Y, Gou M^*. Molecular characterization and expression analysis of a novel cold-inducible RNA-binding protein (CIRBP) gene in lamprey (Lethenteron reissneri). Dev Genes Evol. 2023 Jun;233(1):49-57. doi: 10.1007/s00427-022-00700-8. Epub 2023 Jan 19. PMID: 36658408.
• Duan X, Luan Y, Wang Y, Wang X, Su P, Li Q, Pang Y, He J, Gou M^*. Tryptophan metabolism can modulate immunologic tolerance in primitive vertebrate lamprey via IDO-kynurenine-AHR pathway. Fish Shellfish Immunol. 2023 Jan;132:108485. doi: 10.1016/j.fsi.2022.108485. Epub 2022 Dec 12. PMID: 36521804.
• Teng H^#, Li Q^#, Gou M^#, Liu G, Cao X, Lu J, Han Y, Yu Y, Gao Z, Song X, Dong W, Pang Y. Lamprey immunity protein enables early detection and recurrence monitoring for bladder cancer through recognizing Neu5Gc-modified uromodulin glycoprotein in urine. Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1;1868(12):166493. doi: 10.1016/j.bbadis.2022.166493. Epub 2022 Jul 16. PMID: 35853560.
• Luan Y, Dong Y, Duan X, Wang X, Pang Y, Li Q, Gou M^*. TMT-based quantitative proteomics reveals protein biomarkers from cultured Pacific abalone (Haliotis discus hannai) in different regions. Food Chem X. 2022 Jun 3;14:100355. doi: 10.1016/j.fochx.2022.100355. PMID: 35693453; PMCID: PMC9184861.
• Dong Y, Kazachkova Y, Gou M, Morgan L, Wachsman T, Gazit E, Birkler RID. RawHummus: an R Shiny app for automated raw data quality control in metabolomics. Bioinformatics. 2022 Mar 28;38(7):2072-2074. doi: 10.1093/bioinformatics/btac040. PMID: 35080628.
• Ma L^#, Gou M^#, Du Z, Zhu T, Li J, Li QW, Pang Y. MicroRNA expression profile in Lampetra morii upon Vibrio anguillarum infection and miR-4561 characterization targeting lip. Commun Biol. 2021 Aug 20;4(1):995. doi: 10.1038/s42003-021-02525-z. PMID: 34417547; PMCID: PMC8379177.
• Duan X, Lv M, Liu A, Pang Y, Li Q, Su P, Gou M^*. Identification and evolution of transcription factors RHR gene family (NFAT and RBPJ) involving lamprey (Lethenteron reissneri) innate immunity. Mol Immunol. 2021 Oct;138:38-47. doi: 10.1016/j.molimm.2021.07.017. Epub 2021 Jul 28. PMID: 34332184.
• Ma A^#, Gou M^#, Song T, Li J, Zhu Y, Pang Y, Li Q. Genomic analysis and functional characterization of immune genes from the RIG-I- and MAVS-mediated antiviral signaling pathway in lamprey. Genomics. 2021 Jul;113(4):2400-2412. doi: 10.1016/j.ygeno.2021.04.030. Epub 2021 Apr 19. PMID: 33887365.
• Men L, Li Y, Wang X, Li R, Zhang T, Meng X, Liu S, Gong X, Gou M^*. Protein biomarkers associated with frozen Japanese puffer fish (Takifugu rubripes) quality traits. Food Chem. 2020 Oct 15;327:127002. doi: 10.1016/j.foodchem.2020.127002. Epub 2020 May 7. PMID: 32438262.
• Gou M^#, Ma L, Lu J, Wang X, Pang Y, Li Q. Comparative transcriptomic analysis provides insights into immune responses of lamprey larvae under three pathogens infections. Mol Immunol. 2020 Jan;117:147-154. doi: 10.1016/j.molimm.2019.11.006. Epub 2019 Nov 29. PMID: 31790863.
• Wang D^#, Gou M^#, Hou J, Pang Y, Li Q. The role of serpin protein on the natural immune defense against pathogen infection in Lampetra japonica. Fish Shellfish Immunol. 2019 Sep;92:196-208. doi: 10.1016/j.fsi.2019.05.062. Epub 2019 Jun 5. PMID: 31176010.
• Pang Y^#, Gou M^#, Yang K, Lu J, Han Y, Teng H, Li C, Wang H, Liu C, Zhang K, Yang Y, Li Q. Crystal structure of a cytocidal protein from lamprey and its mechanism of action in the selective killing of cancer cells. Cell Commun Signal. 2019 May 27;17(1):54. doi: 10.1186/s12964-019-0358-y. PMID: 31133022; PMCID: PMC6537362.
• Li Y, Pan J, Gou M^*. The Anti-Proliferation, Cycle Arrest and Apoptotic Inducing Activity of Peperomin E on Prostate Cancer PC-3 Cell Line. Molecules. 2019 Apr 15;24(8):1472. doi: 10.3390/molecules24081472. PMID: 30991627; PMCID: PMC6514592.

开设课程

• 研究生课程
• 高级生物化学
• 现代生物研究技术

科研课题

• 基于蛋白质组学分析大连本地和南方养殖皱纹盘鲍品质和口感差异的研究，大连市科技之星项目支持计划，2019.12，10万元，主持
• 七鳃鳗血清O-乙酰氨基葡萄糖和磷酸化修饰蛋白质组学研究，辽宁省教育厅项目，2019.7，3万元，主持。
• 刺参品质分析合作研究，横向项目， 2014.10， 4万元，主持